Nomegestrol acetate
Modify Date: 2024-01-10 13:00:43
Nomegestrol acetate structure
|
Common Name | Nomegestrol acetate | ||
|---|---|---|---|---|
| CAS Number | 58652-20-3 | Molecular Weight | 370.482 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 507.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C23H30O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 219.8±30.2 °C | |
| Symbol |
GHS08, GHS09 |
Signal Word | Warning | |
Use of Nomegestrol acetateNomegestrol acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors[1]. |
| Name | Nomegestrol acetate |
|---|---|
| Synonym | More Synonyms |
| Description | Nomegestrol acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors[1]. |
|---|---|
| Related Catalog | |
| Target |
Progesterone receptor[1] |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 507.3±50.0 °C at 760 mmHg |
| Molecular Formula | C23H30O4 |
| Molecular Weight | 370.482 |
| Flash Point | 219.8±30.2 °C |
| Exact Mass | 370.214417 |
| PSA | 60.44000 |
| LogP | 3.34 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.554 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS08, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H361fd-H400 |
| Precautionary Statements | P280 |
| Hazard Codes | N |
| Risk Phrases | 63-50 |
| Safety Phrases | 61 |
| RIDADR | UN 3077 9 / PGIII |
| RTECS | RC8899200 |
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Changing convention in combination oral contraceptives: estradiol and nomegestrol acetate in a monophasic 24/4 regimen.
J. Fam. Plann. Reprod. Health Care 39(3) , 211-6, (2013) Initial oral contraceptive regimens were characterised by high doses of ethinylestradiol (EE) and a progestogen in a 21-day regimen that either included seven additional hormone-free tablets or simply... |
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A new contraceptive pill containing 17β-estradiol and nomegestrol acetate.
Womens. Health (Lond. Engl.) 9(1) , 13-23, (2013) Most combined oral contraceptive pills contain ethinyl estradiol (EE) with progestins. In order to minimize the pill's cardiovascular risks, the concept of using 17β-estradiol (E2), the endogenous est... |
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The “newer” progestogens and postmenopausal hormone therapy (HRT)
J. Steroid Biochem. Mol. Biol. 142 , 48-51, (2014) • The “newer” progestogens have a high bioavailability. • The “newer” progestogens have a sufficient progestogenic effect. • The “newer” progestogens do not cause undue side effects. • The “newer” pro... |
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