Fosmidomycin sodium salt
Fosmidomycin sodium salt structure
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Common Name | Fosmidomycin sodium salt | ||
|---|---|---|---|---|
| CAS Number | 66508-37-0 | Molecular Weight | 205.08 | |
| Density | N/A | Boiling Point | 463.7ºC at 760 mmHg | |
| Molecular Formula | C4H9NNaO5P | Melting Point | 189-191ºC | |
| MSDS | N/A | Flash Point | 234.3ºC | |
Use of Fosmidomycin sodium saltFosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial drug, which is active against both Gram-negative and Gram-positive bacteria. |
| Name | Fosmidomycin Sodium Salt |
|---|---|
| Synonym | More Synonyms |
| Description | Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial drug, which is active against both Gram-negative and Gram-positive bacteria. |
|---|---|
| Related Catalog | |
| In Vitro | Fosmidomycin sodium salt is a phosphonic acid antibiotic[1][2], which is active against both Gram-negative and Gram-positive bacteria[3]. |
| In Vivo | Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured[3]. |
| References |
| Boiling Point | 463.7ºC at 760 mmHg |
|---|---|
| Melting Point | 189-191ºC |
| Molecular Formula | C4H9NNaO5P |
| Molecular Weight | 205.08 |
| Flash Point | 234.3ºC |
| PSA | 82.70000 |
| LogP | 0.34710 |
| Storage condition | -20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| HS Code | 2931900090 |
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|
~39%
Fosmidomycin so... CAS#:66508-37-0 |
| Literature: Suresh, Surisetti; Shyamraj, Dharavath; Larhed, Mats Tetrahedron, 2013 , vol. 69, # 3 p. 1183 - 1188 |
|
~%
Fosmidomycin so... CAS#:66508-37-0 |
| Literature: US6680308 B1, ; Page column 15, 16 ; |
|
~95%
Fosmidomycin so... CAS#:66508-37-0 |
| Literature: Yazawa, Hisatoyo; Goto, Shunsuke Tetrahedron Letters, 1985 , vol. 26, # 31 p. 3703 - 3706 |
|
~68%
Fosmidomycin so... CAS#:66508-37-0 |
| Literature: Hemmi; Takeno; Hashimoto; Kamiya Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 111 - 118 |
|
~%
Fosmidomycin so... CAS#:66508-37-0 |
| Literature: Suresh, Surisetti; Shyamraj, Dharavath; Larhed, Mats Tetrahedron, 2013 , vol. 69, # 3 p. 1183 - 1188 |
|
~%
Fosmidomycin so... CAS#:66508-37-0 |
| Literature: US4206156 A1, ; |
| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
| Sodium hydrogen [(2S,3R)-3-methyl-2-oxiranyl]phosphonate |
| sodium,3-[formyl(hydroxy)amino]propyl-hydroxyphosphinate |
| Phosphonic acid, [(2S,3R)-3-methyloxiranyl]-, sodium salt (1:1) |