BC-11-38

Modify Date: 2024-01-04 21:20:22

BC-11-38 Structure
BC-11-38 structure
Common Name BC-11-38
CAS Number 686770-80-9 Molecular Weight 304.43000
Density N/A Boiling Point N/A
Molecular Formula C15H16N2OS2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BC-11-38


BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells[1].

 Names

Name bc11-38
Synonym More Synonyms

 BC-11-38 Biological Activity

Description BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells[1].
Related Catalog
Target

PDE11:0.28 μM (IC50)

In Vitro BC11-38 (20 μM; hours) elevate cAMP levels in H295R adrenocortical cells[1].
References

[1]. Ceyhan O, et al. Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen. Chem Biol. 2012;19(1):155-163.

 Chemical & Physical Properties

Molecular Formula C15H16N2OS2
Molecular Weight 304.43000
Exact Mass 304.07000
PSA 85.49000
LogP 3.38280

 Synonyms

bc 11-38