3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE
Modify Date: 2024-01-12 06:41:47
3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE structure
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Common Name | 3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE | ||
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| CAS Number | 69504-14-9 | Molecular Weight | 381.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H27N5O4Si | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
| Name | [(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-3-hydroxy-5-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxy]oxolan-2-yl]-dimethylsilicon |
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| Synonym | More Synonyms |
| Description | 3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C16H27N5O4Si |
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| Molecular Weight | 381.50 |
| Exact Mass | 381.18300 |
| PSA | 128.54000 |
| LogP | 1.63070 |
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~88%
3'-O-TERT-BUTYL... CAS#:69504-14-9 |
| Literature: Hwu, Jih Ru; Jain, Moti L.; Tsai, Fu-Yuan; Tsay, Shwu-Chen; Balakumar, Arumugham; Hakimelahi, Gholam H. Journal of Organic Chemistry, 2000 , vol. 65, # 17 p. 5077 - 5088 |
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~%
3'-O-TERT-BUTYL... CAS#:69504-14-9 |
| Literature: Ogilvie, Kelvin K.; Entwistle, Douglas W. Carbohydrate Research, 1981 , vol. 89, p. 203 - 210 |
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~75%
3'-O-TERT-BUTYL... CAS#:69504-14-9 |
| Literature: Chandra, Tilak; Broderick, William E.; Broderick, Joan B. Nucleosides, Nucleotides and Nucleic Acids, 2009 , vol. 28, # 11-12 p. 1016 - 1029 |
| Precursor 2 | |
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| DownStream 0 | |
| O3'-(tert-butyl-dimethyl-silanyl)-adenosine |
| 3'-O-(tert-butyldimethylsilyl)adenosine |