Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

69504-14-9

69504-14-9 structure

Name: 3'-O-TERT-BUTYLDIMETHYLSILYLADENOSINE
Chemical Name: [(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-3-hydroxy-5-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxy]oxolan-2-yl]-dimethylsilicon
CAS Number: 69504-14-9
Molecular Formula: C₁₆H₂₇N₅O₄Si
Molecular Weight: 381.50
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-11-24 20:38:43
Modify Date: 2024-01-12 06:41:47
3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Name	[(2S,3R,4S,5R)-2-(6-aminopurin-9-yl)-3-hydroxy-5-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxy]oxolan-2-yl]-dimethylsilicon
Synonyms	O3'-(tert-butyl-dimethyl-silanyl)-adenosine 3'-O-(tert-butyldimethylsilyl)adenosine

Description	3’-O-t-Butyldimethylsilyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Molecular Formula	C₁₆H₂₇N₅O₄Si
Molecular Weight	381.50
Exact Mass	381.18300
PSA	128.54000
LogP	1.63070

69504-03-6

~88%

69504-14-9

Literature: Hwu, Jih Ru; Jain, Moti L.; Tsai, Fu-Yuan; Tsay, Shwu-Chen; Balakumar, Arumugham; Hakimelahi, Gholam H. Journal of Organic Chemistry, 2000 , vol. 65, # 17 p. 5077 - 5088

69504-13-8

69504-14-9

Literature: Ogilvie, Kelvin K.; Entwistle, Douglas W. Carbohydrate Research, 1981 , vol. 89, p. 203 - 210

1237843-27-4

~75%

69504-14-9

Literature: Chandra, Tilak; Broderick, William E.; Broderick, Joan B. Nucleosides, Nucleotides and Nucleic Acids, 2009 , vol. 28, # 11-12 p. 1016 - 1029

Precursor 2
69504-03-6 69504-13-8
DownStream 0

69504-14-9	69504-11-6
120957-59-7	51549-31-6
129801-99-6	823791-01-1
823791-02-2	140226-13-7
198267-31-1	90827-37-5
1158522-08-7	940364-43-2
134104-43-1	2757922-84-0
131615-57-1	2451247-95-1
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4