Irinotecan-d10

Modify Date: 2024-01-14 18:48:27

Irinotecan-d10 Structure
Irinotecan-d10 structure
Common Name Irinotecan-d10
CAS Number 718613-28-6 Molecular Weight 596.74
Density N/A Boiling Point N/A
Molecular Formula C33H28D10N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Irinotecan-d10


Irinotecan-d10 ((+)-Irinotecan-d10) is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1].

 Names

Name Irinotecan-d10

 Irinotecan-d10 Biological Activity

Description Irinotecan-d10 ((+)-Irinotecan-d10) is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1].
Related Catalog
References

[1]. Morales C, et al. Antitumoral effect of irinotecan (CPT-11) on an experimental model of malignant neuroectodermal tumor. J Neurooncol. 2002 Feb;56(3):219-26.

 Chemical & Physical Properties

Molecular Formula C33H28D10N4O6
Molecular Weight 596.74