4-thiothymidine

Modify Date: 2024-01-11 23:29:38

4-thiothymidine Structure
4-thiothymidine structure
Common Name 4-thiothymidine
CAS Number 7236-57-9 Molecular Weight 258.29
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H14N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-thiothymidine


4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name Thymidine, 4-thio
Synonym More Synonyms

 4-thiothymidine Biological Activity

Description 4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C10H14N2O4S
Molecular Weight 258.29
Exact Mass 258.067413
PSA 119.57000
LogP -0.07
Index of Refraction 1.672

 Safety Information

Hazard Codes Xi

 Synonyms

deoxy-4-thiothymidine
4-thio-thymidine
4-Thio-thymidin
2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4-dihydro-5-methyl-4-thioxo-
4-thiothymidine
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
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