7236-57-9

7236-57-9 structure

Name: 4-thiothymidine
Chemical Name: Thymidine, 4-thio
CAS Number: 7236-57-9
Molecular Formula: C₁₀H₁₄N₂O₄S
Molecular Weight: 258.29
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-18 12:04:09
Modify Date: 2024-01-11 23:29:38
4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	Thymidine, 4-thio
Synonyms	deoxy-4-thiothymidine 4-thio-thymidine 4-Thio-thymidin 2(1H)-Pyrimidinone, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4-dihydro-5-methyl-4-thioxo- 4-thiothymidine 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone

Description	4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Hazard Codes	Xi