Oxypeucedanin structure
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Common Name | Oxypeucedanin | ||
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CAS Number | 737-52-0 | Molecular Weight | 286.279 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 469.6±45.0 °C at 760 mmHg | |
Molecular Formula | C16H14O5 | Melting Point | 141-142 °C | |
MSDS | N/A | Flash Point | 237.8±28.7 °C |
Use of OxypeucedaninOxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation[1]. Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration[2]. |
Name | oxypeucedanin |
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Synonym | More Synonyms |
Description | Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation[1]. Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration[2]. |
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Related Catalog | |
Target |
IC50: HKv1.5 current; apoptosis[1] |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 469.6±45.0 °C at 760 mmHg |
Melting Point | 141-142 °C |
Molecular Formula | C16H14O5 |
Molecular Weight | 286.279 |
Flash Point | 237.8±28.7 °C |
Exact Mass | 286.084137 |
PSA | 65.11000 |
LogP | 2.17 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.634 |
Storage condition | 2-8°C |
Hazard Codes | Xi |
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~86% Oxypeucedanin CAS#:737-52-0 |
Literature: Row; Brown; Stachulski; Lennard Organic and Biomolecular Chemistry, 2006 , vol. 4, # 8 p. 1604 - 1610 |
~% Oxypeucedanin CAS#:737-52-0 |
Literature: Organic and Biomolecular Chemistry, , vol. 4, # 8 p. 1604 - 1610 |
~% Oxypeucedanin CAS#:737-52-0 |
Literature: Organic and Biomolecular Chemistry, , vol. 4, # 8 p. 1604 - 1610 |
~% Oxypeucedanin CAS#:737-52-0 |
Literature: Organic and Biomolecular Chemistry, , vol. 4, # 8 p. 1604 - 1610 |
4-(3,3-Dimethyl-oxiranylmethoxy)-furo[3,2-g]chromen-7-one |
7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3,3-dimethyloxiranyl)methoxy)- |
5-[(3,3-Dimethyl-2-oxiranyl)methoxy]-7H-furo[3,2-g]chromen-7-one |
4-[(3,3-Dimethyl-2-oxiranyl)methoxy]-7H-furo[3,2-g]chromen-7-one |
7H-Furo[3,2-g][1]benzopyran-7-one, 5-[(3,3-dimethyloxiranyl)methoxy]- |
7H-Furo[3,2-g][1]benzopyran-7-one, 4-[(3,3-dimethyloxiranyl)methoxy]- |
Oxypencedanin |
5-[(3,3-Dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one |
oxypeucadanin |