5-Geranoxy-7-methoxycoumarin structure
|
Common Name | 5-Geranoxy-7-methoxycoumarin | ||
---|---|---|---|---|
CAS Number | 7380-39-4 | Molecular Weight | 328.40 | |
Density | 1.092g/cm3 | Boiling Point | 487.1ºC at 760 mmHg | |
Molecular Formula | C20H24O4 | Melting Point | 86-88ºC | |
MSDS | N/A | Flash Point | 213.2ºC |
Use of 5-Geranoxy-7-methoxycoumarin5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis[1][2]. |
Name | 5-[(2E)-3,7-dimethylocta-2,6-dienoxy]-7-methoxychromen-2-one |
---|---|
Synonym | More Synonyms |
Description | 5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis[1][2]. |
---|---|
Related Catalog | |
In Vitro | 5-Geranoxy-7-methoxycoumarin (12.5-200 µM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells[1]. 5-Geranoxy-7-methoxycoumarin (50 µM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells[1]. 5-Geranoxy-7-methoxycoumarin (50 µM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation[1]. Cell Proliferation Assay[1] Cell Line: SW480 Concentration: 0-20 μM Incubation Time: 24, 48 and 72 hours Result: Inhibited cell growth by 67% at 72 hours. Apoptosis Analysis[1] Cell Line: SW480 cells Concentration: 50 μM Incubation Time: 48 hours Result: Induced cell apoptosis. Cell Cycle Analysis[1] Cell Line: SW480 cells Concentration: 50 μM Incubation Time: 48 hours Result: Inhibited cell cycle progression in vitro. |
References |
Density | 1.092g/cm3 |
---|---|
Boiling Point | 487.1ºC at 760 mmHg |
Melting Point | 86-88ºC |
Molecular Formula | C20H24O4 |
Molecular Weight | 328.40 |
Flash Point | 213.2ºC |
Exact Mass | 328.16700 |
PSA | 48.67000 |
LogP | 4.87310 |
Index of Refraction | 1.542 |
Storage condition | -20°C |
5-Geranoxy-7-methoxy-cumarin |
5-geranyloxy-7-methoxycoumarin |
5-Geranoxy-7-methoxycoumarin |
7-Methoxy-5-geranoxycoumarin |