Mosloflavone structure
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Common Name | Mosloflavone | ||
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CAS Number | 740-33-0 | Molecular Weight | 298.290 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 508.5±50.0 °C at 760 mmHg | |
Molecular Formula | C17H14O5 | Melting Point | 163-164ºC (chloroform , acetone ) | |
MSDS | N/A | Flash Point | 190.5±23.6 °C |
Use of MosloflavoneMosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with anti-EV71 activity. Mosloflavone inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation. |
Name | 5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one |
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Synonym | More Synonyms |
Description | Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with anti-EV71 activity. Mosloflavone inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation. |
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Related Catalog | |
Target |
IC50: EV71; bacterial[1][2] |
In Vitro | Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases[2]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 508.5±50.0 °C at 760 mmHg |
Melting Point | 163-164ºC (chloroform , acetone ) |
Molecular Formula | C17H14O5 |
Molecular Weight | 298.290 |
Flash Point | 190.5±23.6 °C |
Exact Mass | 298.084137 |
PSA | 68.90000 |
LogP | 2.74 |
Vapour Pressure | 0.0±1.4 mmHg at 25°C |
Index of Refraction | 1.622 |
HS Code | 2914509090 |
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Precursor 9 | |
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DownStream 3 | |
HS Code | 2914509090 |
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Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
5-hydroxy-6,7-dimethoxy-2-phenylchromen-4-one |
5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one |
baicalein 6,7-dimethyl ether |
4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-phenyl- |
Mosloflavone |
5-hydroxy-6,7-dimethoxyflavone |