α-Conotoxin GI

Modify Date: 2024-01-07 19:09:54

α-Conotoxin GI structure	Common Name	α-Conotoxin GI
	CAS Number	76862-65-2	Molecular Weight	1437.61
	Density	1.71	Boiling Point	N/A
	Molecular Formula	C₅₅H₈₀N₂₀O₁₈S₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of α-Conotoxin GI

α-Conotoxin GI has high affinity for nAChR.α-Conotoxin GI is a short peptide toxin that can be isolated from the venom of Conus geographus.α-Conotoxin GI has the similar activity with neuromuscular blocking agent[1][2][3].

Name	α-CONOTOXIN GI
Synonym	More Synonyms

Description	α-Conotoxin GI has high affinity for nAChR.α-Conotoxin GI is a short peptide toxin that can be isolated from the venom of Conus geographus.α-Conotoxin GI has the similar activity with neuromuscular blocking agent[1][2][3].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. Groebe DR, et al. Determinants involved in the affinity of alpha-conotoxins GI and SI for the muscle subtype of nicotinic acetylcholine receptors. Biochemistry. 1997 May 27;36(21):6469-74. [2]. Yu S, et al. Sensitive Detection of α-Conotoxin GI in Human Plasma Using a Solid-Phase Extraction Column and LC-MS/MS. Toxins (Basel). 2017 Jul 28;9(8):235. [3]. Blount K, et al. alpha-Conotoxin GI produces tetanic fade at the rat neuromuscular junction. Toxicon. 1992 Aug;30(8):835-42.

Description

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

Research Areas >> Neurological Disease

References

[1]. Groebe DR, et al. Determinants involved in the affinity of alpha-conotoxins GI and SI for the muscle subtype of nicotinic acetylcholine receptors. Biochemistry. 1997 May 27;36(21):6469-74.

[2]. Yu S, et al. Sensitive Detection of α-Conotoxin GI in Human Plasma Using a Solid-Phase Extraction Column and LC-MS/MS. Toxins (Basel). 2017 Jul 28;9(8):235.

[3]. Blount K, et al. alpha-Conotoxin GI produces tetanic fade at the rat neuromuscular junction. Toxicon. 1992 Aug;30(8):835-42.

Density	1.71
Molecular Formula	C₅₅H₈₀N₂₀O₁₈S₄
Molecular Weight	1437.61
Exact Mass	1436.48000
PSA	722.15000
Storage condition	-20°C

α-Conotoxin GI MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GL1500000

CHEMICAL NAME :: Conotoxin GI

CAS REGISTRY NUMBER :: 76862-65-2

LAST UPDATED :: 199506

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C55-H80-N20-O18-S4

MOLECULAR WEIGHT :: 1437.79

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 ug/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - other changes

REFERENCE :: ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 190,539,1978

Hazard Codes	Xn
RIDADR	UN 3172
Packaging Group	III
Hazard Class	6.1(b)

GLU-CYS-CYS-ASN-PRO-ALA-CYS-GLY-ARG-HIS-TYR-SER-CYS-NH2

a-Conotoxin GI

CONOTOXIN GI

a-Conotoxin GI,Conus geographus

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: α-ConotoxinGI
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

GL Biochem (Shanghai) Ltd.
China
Product Name: α-Conotoxin GI
Price: $Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

Nanjing Peptide Biotech Ltd
China
Product Name: α-Conotoxin GI
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Delivery: 7 Day
Contact: jom
Email: chenglong.fan@njpeptide.com

Taiwan Oyi peptide Co. Ltd
China
Product Name: α-Conotoxin GI
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

Get all suppliers and price by the below link:

α-Conotoxin GI suppliers

α-Conotoxin GI price

α-Conotoxin GI

Use of α-Conotoxin GI

Names

α-Conotoxin GI Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synonyms