Multi-kinase inhibitor 1

Modify Date: 2024-01-07 10:31:59

Multi-kinase inhibitor 1 Structure
Multi-kinase inhibitor 1 structure
Common Name Multi-kinase inhibitor 1
CAS Number 778274-97-8 Molecular Weight 418.369
Density 1.4±0.1 g/cm3 Boiling Point 615.9±55.0 °C at 760 mmHg
Molecular Formula C20H17F3N4O3 Melting Point N/A
MSDS N/A Flash Point 326.3±31.5 °C

 Use of Multi-kinase inhibitor 1


Multi-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl[1].

 Names

Name N-(2-Hydroxyethyl)-4-(6-{[4-(trifluoromethoxy)phenyl]amino}-4-pyrimidinyl)benzamide
Synonym More Synonyms

 Multi-kinase inhibitor 1 Biological Activity

Description Multi-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl[1].
Related Catalog
Target

PDGFR

Bcr-Abl

In Vitro Multi-kinase inhibitor 1 (compound 68) is a potent multi-kinase inhibitor. The protein kinases represent a large family of proteins, which play a central role in the regulation of a wide variety of cellular processes and maintaining control over cellular function. These kinases include receptor tyrosine kinases, such as platelet derived growth factor receptor kinase(PDGF-R), the receptor kinase for stem cell factor, c-Kit, and non-receptor tyrosine kinases, such as the fusion kinase Bcr-abl[1].
References

[1]. Qiang Ding, et al. Novel compounds and compositions as protein kinase inhibitors. WO2004089286A2.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 615.9±55.0 °C at 760 mmHg
Molecular Formula C20H17F3N4O3
Molecular Weight 418.369
Flash Point 326.3±31.5 °C
Exact Mass 418.125275
LogP 3.20
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.600
Storage condition -20℃

 Synonyms

N-(2-Hydroxyethyl)-4-(6-{[4-(trifluoromethoxy)phenyl]amino}-4-pyrimidinyl)benzamide
Benzamide, N-(2-hydroxyethyl)-4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
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