HOOCCH2O-PEG4-CH2COOH

Modify Date: 2024-01-10 11:26:50

HOOCCH2O-PEG4-CH2COOH Structure
HOOCCH2O-PEG4-CH2COOH structure
Common Name HOOCCH2O-PEG4-CH2COOH
CAS Number 77855-75-5 Molecular Weight 310.29800
Density N/A Boiling Point N/A
Molecular Formula C12H22O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HOOCCH2O-PEG4-CH2COOH


HOOCCH2O-PEG4-CH2COOH, compound 5, is a symmetric PEG linker, used for the synthesis of the first class of Homo-PROTAC[1].

 Names

Name 2-[2-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Synonym More Synonyms

 HOOCCH2O-PEG4-CH2COOH Biological Activity

Description HOOCCH2O-PEG4-CH2COOH, compound 5, is a symmetric PEG linker, used for the synthesis of the first class of Homo-PROTAC[1].
Related Catalog
References

[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.

 Chemical & Physical Properties

Molecular Formula C12H22O9
Molecular Weight 310.29800
Exact Mass 310.12600
PSA 120.75000

 Safety Information

Hazard Codes Xi

 Synthetic Route

~99%

HOOCCH2O-PEG4-CH2COOH Structure

HOOCCH2O-PEG4-C...

CAS#:77855-75-5

Literature: Wittmann, Valentin; Takayama, Shuichi; Gong, Ke Wei; Weitz-Schmidt, Gabriele; Wong, Chi-Huey Journal of Organic Chemistry, 1998 , vol. 63, # 15 p. 5137 - 5143

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HOOCCH2O-PEG4-CH2COOH Structure

HOOCCH2O-PEG4-C...

CAS#:77855-75-5

Literature: Wittmann, Valentin; Takayama, Shuichi; Gong, Ke Wei; Weitz-Schmidt, Gabriele; Wong, Chi-Huey Journal of Organic Chemistry, 1998 , vol. 63, # 15 p. 5137 - 5143

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

3,6,9,12,15-pentaoxaheptadecane-1,17-dioic acid
3,6,9,12,15-Pentaoxaheptadecanedioic acid
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Price: ¥650/5 mg

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