Calcifediol-D6
Calcifediol-D6 structure
|
Common Name | Calcifediol-D6 | ||
|---|---|---|---|---|
| CAS Number | 78782-98-6 | Molecular Weight | 406.67400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H38D6O2 | Melting Point | 64-69°C | |
| MSDS | N/A | Flash Point | 14℃ | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
Use of Calcifediol-D6Calcifediol-D6 is the deuterated form of Calcifediol(25-hydroxy Vitamin D3), which is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase IC50 value:Target: This metabolite is being measured by physicians worldwide to determine a patient's vitamin d status.Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. |
| Name | (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol |
|---|---|
| Synonym | More Synonyms |
| Description | Calcifediol-D6 is the deuterated form of Calcifediol(25-hydroxy Vitamin D3), which is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase IC50 value:Target: This metabolite is being measured by physicians worldwide to determine a patient's vitamin d status.Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. |
|---|---|
| Related Catalog | |
| References |
| Melting Point | 64-69°C |
|---|---|
| Molecular Formula | C27H38D6O2 |
| Molecular Weight | 406.67400 |
| Flash Point | 14℃ |
| Exact Mass | 406.37200 |
| PSA | 40.46000 |
| LogP | 6.73390 |
| Storage condition | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| Symbol |
GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H319 |
| Precautionary Statements | P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235 |
| Hazard Codes | F |
| Risk Phrases | 11 |
| Safety Phrases | 7-16 |
| RIDADR | UN1170 - class 3 - PG 2 - Ethanol, solution |
|
~%
Calcifediol-D6 CAS#:78782-98-6 |
| Literature: Tetrahedron Letters, , vol. 32, # 24 p. 2813 - 2816 |
|
~%
Calcifediol-D6 CAS#:78782-98-6 |
| Literature: Tetrahedron Letters, , vol. 32, # 24 p. 2813 - 2816 |
|
~%
Calcifediol-D6 CAS#:78782-98-6 |
| Literature: Tetrahedron Letters, , vol. 32, # 24 p. 2813 - 2816 |
|
~%
Calcifediol-D6 CAS#:78782-98-6 |
| Literature: Tetrahedron Letters, , vol. 32, # 24 p. 2813 - 2816 |
|
~%
Calcifediol-D6 CAS#:78782-98-6 |
| Literature: Tetrahedron Letters, , vol. 32, # 24 p. 2813 - 2816 |
![(1R,3aR,4S,7aR)-Octahydro-1-[(1S)-2-iodo-1-methylethyl]-7a-methyl-1H-inden-4-ol structure](https://image.chemsrc.com/caspic/034/116535-65-0.png)
![tert-Butyl-{3-[2-(diphenyl-phosphinoyl)-ethylidene]-4-methylene-cyclohexyloxy}-dimethyl-silane structure](https://image.chemsrc.com/caspic/214/100858-27-3.png)
![[1R-[1α(R*),3aβ,7aα]]-Octahydro-δ,7a-dimethyl-4-oxo-1H-indene-1-pentanoic Acid Methyl Ester structure](https://image.chemsrc.com/caspic/357/135359-41-0.png)
CAS#:78782-99-7| Hidroferol-d6 |
| Calcidiol-d6 |
| Calcifediol-D6 |
| 25-Hydroxyvitamin D3-d6 |
| 25-Hydroxyvitamin D-d6 |
| Ro 8-8892-d6 |
| <26,27-2H6>-25-hydroxyvitamin D3 |
| Didrogyl-d6 |
| 25-Hydroxycholecalciferol-d6 |