PU 23
Modify Date: 2024-01-05 13:48:33
PU 23 structure
|
Common Name | PU 23 | ||
|---|---|---|---|---|
| CAS Number | 817635-93-1 | Molecular Weight | 425.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H19N3O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PU 23PU 23 is a non-carboxylic multidrug resistance protein 4 (MRP4) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine[1]. |
| Name | PU 23 |
|---|
| Description | PU 23 is a non-carboxylic multidrug resistance protein 4 (MRP4) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 2.81 and 14.11 μM, respectively. The combination of PU 23 (Cpd23) and 6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 1.84 and 6.06 μM, respectively[1]. Preincubation of HEK293/MRP4 cells with PU 23 (50 μM) for 2 h also significantly increases the amount of 6-MP in cells[1]. |
| References |
| Molecular Formula | C21H19N3O3S2 |
|---|---|
| Molecular Weight | 425.52 |
| Storage condition | -20°C |