Valiolamine

Modify Date: 2024-01-02 14:34:46

Valiolamine Structure
Valiolamine structure
Common Name Valiolamine
CAS Number 83465-22-9 Molecular Weight 118.177
Density 1.0±0.1 g/cm3 Boiling Point 249.1±25.0 °C at 760 mmHg
Molecular Formula C7H15NO5 Melting Point N/A
MSDS N/A Flash Point 104.4±23.2 °C

 Use of Valiolamine


Valiolamine, an aminocyclitol has been isolated from the fermentation broth of Streptomyces hygroscopicus subsp. Valiolamine has potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase[1].

 Names

Name (1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
Synonym More Synonyms

 Valiolamine Biological Activity

Description Valiolamine, an aminocyclitol has been isolated from the fermentation broth of Streptomyces hygroscopicus subsp. Valiolamine has potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase[1].
Related Catalog
References

[1]. Y Kameda, et al. Valiolamine, a New Alpha-Glucosidase Inhibiting Aminocyclitol Produced by Streptomyces Hygroscopicus. J Antibiot (Tokyo). 1984 Nov;37(11):1301-7.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 249.1±25.0 °C at 760 mmHg
Molecular Formula C7H15NO5
Molecular Weight 118.177
Flash Point 104.4±23.2 °C
Exact Mass 118.110611
PSA 72.27000
LogP -1.60
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.490

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NM7522300
CHEMICAL NAME :
D-epi-Inositol, 4-amino-3,4-dideoxy-2-C-(hydroxymethyl)-, hydrate
CAS REGISTRY NUMBER :
83465-22-9
LAST UPDATED :
199303
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H15-N-O5.H2-O
MOLECULAR WEIGHT :
211.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #63456

 Safety Information

HS Code 2922199090

 Synthetic Route

 Customs

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

1-Butanol, 2,4-diamino-3-methyl-, (2S)-
(2S)-2,4-Diamino-3-methyl-1-butanol
Valiolamine hydrate
Valinolamine
valiolamine
MFCD07773061
(1S,2S,3R,4S,5S)-5-AMINO-1-HYDROXYMETHYL-CYCLOHEXANE-1,2,3,4-TETRAOL
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