1,3-Dipropyl-8-phenylxanthine

Modify Date: 2024-02-24 18:07:28

1,3-Dipropyl-8-phenylxanthine Structure
1,3-Dipropyl-8-phenylxanthine structure
Common Name 1,3-Dipropyl-8-phenylxanthine
CAS Number 85872-53-3 Molecular Weight 312.36600
Density 1.218g/cm3 Boiling Point 539.1ºC at 760 mmHg
Molecular Formula C17H20N4O2 Melting Point N/A
MSDS N/A Flash Point 279.8ºC

 Use of 1,3-Dipropyl-8-phenylxanthine


NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].

 Names

Name 1,3-Dipropyl-8-phenylxanthine
Synonym More Synonyms

 1,3-Dipropyl-8-phenylxanthine Biological Activity

Description NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].
Related Catalog
References

[1]. P. V. Kaplita, et al. NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays. , 20(4), 429–443.

 Chemical & Physical Properties

Density 1.218g/cm3
Boiling Point 539.1ºC at 760 mmHg
Molecular Formula C17H20N4O2
Molecular Weight 312.36600
Flash Point 279.8ºC
Exact Mass 312.15900
PSA 72.68000
LogP 2.37330
Index of Refraction 1.587

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UO8430880
CHEMICAL NAME :
1H-Purine-2,6,dione, 3,7-dihydro-1,3-dipropyl-8-phenyl-
CAS REGISTRY NUMBER :
85872-53-3
LAST UPDATED :
199806
DATA ITEMS CITED :
1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5032593

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

dione,3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-6
3,9-Dihydro-8-phenyl-1,3-dipropyl-1H-purine-2,6-dione
1,3-dipropyl-8-phenyl xanthine
NPC-200
3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-2,6,dione
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