85872-53-3

85872-53-3 structure
85872-53-3 structure
  • Name: 1,3-Dipropyl-8-phenylxanthine
  • Chemical Name: 1,3-Dipropyl-8-phenylxanthine
  • CAS Number: 85872-53-3
  • Molecular Formula: C17H20N4O2
  • Molecular Weight: 312.36600
  • Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
  • Create Date: 2018-08-28 07:46:07
  • Modify Date: 2024-02-24 18:07:28
  • NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].

Name 1,3-Dipropyl-8-phenylxanthine
Synonyms dione,3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-6
3,9-Dihydro-8-phenyl-1,3-dipropyl-1H-purine-2,6-dione
1,3-dipropyl-8-phenyl xanthine
NPC-200
3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-2,6,dione
Description NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].
Related Catalog
References

[1]. P. V. Kaplita, et al. NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays. , 20(4), 429–443.

Density 1.218g/cm3
Boiling Point 539.1ºC at 760 mmHg
Molecular Formula C17H20N4O2
Molecular Weight 312.36600
Flash Point 279.8ºC
Exact Mass 312.15900
PSA 72.68000
LogP 2.37330
Index of Refraction 1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UO8430880
CHEMICAL NAME :
1H-Purine-2,6,dione, 3,7-dihydro-1,3-dipropyl-8-phenyl-
CAS REGISTRY NUMBER :
85872-53-3
LAST UPDATED :
199806
DATA ITEMS CITED :
1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5032593
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%