GR 125487 sulfamate

Modify Date: 2024-10-20 22:55:30

GR 125487 sulfamate Structure
GR 125487 sulfamate structure
Common Name GR 125487 sulfamate
CAS Number 859502-43-5 Molecular Weight 524.58
Density N/A Boiling Point N/A
Molecular Formula C19H29FN4O8S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GR 125487 sulfamate


GR125487 sulfamate is an orally active and selective antagonist of 5-HT4R. GR125487 sulfamate effectively blocks the cognition enhancing effect. GR125487 sulfamate can be used to study memory disorders, gastrointestinal disorders, mood disorders and urinary tract dysfunction[1].

 Names

Name Sulfamic acid-(1-{2-[(methylsulfonyl)amino]ethyl}-4-piperidinyl )methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate (1:1)
Synonym More Synonyms

 GR 125487 sulfamate Biological Activity

Description GR125487 sulfamate is an orally active and selective antagonist of 5-HT4R. GR125487 sulfamate effectively blocks the cognition enhancing effect. GR125487 sulfamate can be used to study memory disorders, gastrointestinal disorders, mood disorders and urinary tract dysfunction[1].
Related Catalog
References

[1]. Nirogi, R., et al. Synthesis of GR 125487, a selective 5-HT4receptor antagonist. Synthetic Communications, 46(12), 1036–1043.

 Chemical & Physical Properties

Molecular Formula C19H29FN4O8S2
Molecular Weight 524.58
Exact Mass 524.14100
PSA 197.88000
LogP 3.67220

 Synonyms

[Ala92]-p16 (84-103)
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