RSV-IN-1

Modify Date: 2024-01-06 00:10:11

Use of RSV-IN-1

RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC50 of 0.11 μM.

Name	RSV-IN-1
Synonym	More Synonyms

Description	RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC50 of 0.11 μM.
Related Catalog	Signaling Pathways >> Anti-infection >> RSV Research Areas >> Infection
Target	IC50: 0.11μM (hRSV)[1].
In Vitro	The concentration of P13 that reduces the number of RSV plaques in HEp-2 cells by 50% (IC50) is 0.11 μM. The concentration of P13 that reduces the viability of HEp-2 by 50% (CC50) is 310 μM. Note that some cytotoxicity of P13 observed at 500 μM might be due to DMSO solvent. Hence, the selective index (CC50/IC50) values is 2818 for P13. Note that even at the relatively high concentrations P13 does not completely block the development of RSV plaques. These escape plaques are of smaller size and of non-syncytial phenotype as compared to plaques formed in the absence of inhibitor[1].
References	[1]. Lundin A, et al. Two novel fusion inhibitors of human respiratory syncytial virus. Antiviral Res. 2010 Dec;88(3):317-24.

Benzenesulfonamide, N-(2-hydroxyethyl)-4-methoxy-N-methyl-3-(6-methyl-1,2,4-triazolo[3,4-a]phthalazin-3-yl)-

N-(2-Hydroxyethyl)-4-methoxy-N-methyl-3-(6-methyl[1,2,4]triazolo[3,4-a]phthalazin-3-yl)benzenesulfonamide

Get all suppliers and price by the below link:

Price: ￥7590/10 mM * 1 mL in DMSO

Reference only. check more RSV-IN-1 price