Anti-inflammatory agent 34

Modify Date: 2024-01-02 16:10:29

Anti-inflammatory agent 34 structure	Common Name	Anti-inflammatory agent 34
	CAS Number	867301-81-3	Molecular Weight	324.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₂N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Anti-inflammatory agent 34

Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].

Name	Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro-

Description	Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Anti-inflammatory agent 34 (Compound IVf) (200mg/kg; p.o.; single dose) 对角叉菜胶诱导的大鼠足水肿有抑制作用，对小鼠有缓解疼痛作用[1]。 Animal Model: Male albino rats, carrageenan-induced rat paw edema assay model[1] Dosage: 200 mg/kg Administration: Oral, single dose Result: Showed 55.7 ± 0.019% inhibition on carrageenan induced rat paw edema at the 3rd h. Animal Model: Albino mice, acetic acid induced writhing method[1] Dosage: 200 mg/kg Administration: Oral, single dose Result: Showed 48.1% analgesic activity.
References	[1]. Ronad PM, et al. Synthesis and evaluation of anti-inflammatory and analgesic activities of a novel series of substituted-N-(4-methyl-2-oxo-2H-chromen-7-yl) benzamides. Arzneimittelforschung. 2008;58(12):641-6.

Molecular Formula	C₁₇H₁₂N₂O₅
Molecular Weight	324.29