867301-81-3

867301-81-3 structure
867301-81-3 structure
  • Name: Anti-inflammatory agent 34
  • Chemical Name: Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro-
  • CAS Number: 867301-81-3
  • Molecular Formula: C17H12N2O5
  • Molecular Weight: 324.29
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2022-08-11 19:18:32
  • Modify Date: 2024-01-02 16:10:29
  • Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].

Name Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro-
Description Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].
Related Catalog
In Vivo Anti-inflammatory agent 34 (Compound IVf) (200mg/kg; p.o.; single dose) 对角叉菜胶诱导的大鼠足水肿有抑制作用,对小鼠有缓解疼痛作用[1]。 Animal Model: Male albino rats, carrageenan-induced rat paw edema assay model[1] Dosage: 200 mg/kg Administration: Oral, single dose Result: Showed 55.7 ± 0.019% inhibition on carrageenan induced rat paw edema at the 3rd h. Animal Model: Albino mice, acetic acid induced writhing method[1] Dosage: 200 mg/kg Administration: Oral, single dose Result: Showed 48.1% analgesic activity.
References

[1]. Ronad PM, et al. Synthesis and evaluation of anti-inflammatory and analgesic activities of a novel series of substituted-N-(4-methyl-2-oxo-2H-chromen-7-yl) benzamides. Arzneimittelforschung. 2008;58(12):641-6.  

Molecular Formula C17H12N2O5
Molecular Weight 324.29