m-PEG4-CH2-acid

Modify Date: 2024-01-09 23:54:35

m-PEG4-CH2-acid Structure
m-PEG4-CH2-acid structure
Common Name m-PEG4-CH2-acid
CAS Number 874208-84-1 Molecular Weight 250.29
Density N/A Boiling Point N/A
Molecular Formula C11H22O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG4-CH2-acid


m-PEG4-CH2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG4-(CH2)3-acid

 m-PEG4-CH2-acid Biological Activity

Description m-PEG4-CH2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zuluaga MF, et al. Enhanced prostate cancer targeting by modified protease sensitive photosensitizer prodrugs. Mol Pharm. 2012 Jun 4;9(6):1570-9.

 Chemical & Physical Properties

Molecular Formula C11H22O6
Molecular Weight 250.29
Storage condition 2-8°C
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