874208-84-1

874208-84-1 structure

Name: m-PEG4-CH2-acid
Chemical Name: m-PEG4-(CH2)3-acid
CAS Number: 874208-84-1
Molecular Formula: C₁₁H₂₂O₆
Molecular Weight: 250.29
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-08 12:40:43
Modify Date: 2024-01-09 23:54:35
m-PEG4-CH2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	m-PEG4-(CH2)3-acid

Description	m-PEG4-CH2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Zuluaga MF, et al. Enhanced prostate cancer targeting by modified protease sensitive photosensitizer prodrugs. Mol Pharm. 2012 Jun 4;9(6):1570-9.