VPC-80051(VPC80051)

Modify Date: 2024-01-21 07:20:20

VPC-80051(VPC80051) Structure
VPC-80051(VPC80051) structure
Common Name VPC-80051(VPC80051)
CAS Number 877969-69-2 Molecular Weight 301.297
Density N/A Boiling Point N/A
Molecular Formula C16H13F2N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VPC-80051(VPC80051)


VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1; interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line, reduces AR-V7 mRNA levels.

 Names

Name VPC-80051

 VPC-80051(VPC80051) Biological Activity

Description VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1; interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line, reduces AR-V7 mRNA levels.
References References 1. Carabet LA, et al. Molecules. 2019 Feb 20;24(4). pii: E763. View Related Products by Target Spliceosome

 Chemical & Physical Properties

Molecular Formula C16H13F2N3O
Molecular Weight 301.297
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