PROTAC BRD9-binding moiety 5
Modify Date: 2024-07-17 10:55:43
PROTAC BRD9-binding moiety 5 structure
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Common Name | PROTAC BRD9-binding moiety 5 | ||
|---|---|---|---|---|
| CAS Number | 893633-37-9 | Molecular Weight | 346.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H18N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC BRD9-binding moiety 5PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells[1]. |
| Name | PROTAC BRD9-binding moiety 5 |
|---|
| Description | PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells[1]. |
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| Related Catalog | |
| Target |
BRD9:4.2 μM (IC50) |
| In Vitro | PROTAC BRD9-binding moiety 5 (compound 7) (0-250 μM; 48h) has antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116[1]. Cell Proliferation Assay[1] Cell Line: Jurkat, MDA-MB-231, A375 and HCT-116 Concentration: 0-250 μM Incubation Time: 48h Result: Exhibited antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116 with IC50s of 77 ± 7 μM, 125 ± 8 μM, 133 ± 5 μM and 145 ± 3 μM. |
| References |
| Molecular Formula | C19H18N6O |
|---|---|
| Molecular Weight | 346.39 |