Imidapril
Modify Date: 2024-01-13 20:22:12
Imidapril structure
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Common Name | Imidapril | ||
|---|---|---|---|---|
| CAS Number | 89371-37-9 | Molecular Weight | 405.44500 | |
| Density | 1.266 g/cm3 | Boiling Point | 577ºC at 760 mmHg | |
| Molecular Formula | C20H27N3O6 | Melting Point | 195-197°C | |
| MSDS | N/A | Flash Point | 302.8ºC | |
Use of ImidaprilImidapril (TA-6366 free base) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research[1][2]. |
| Name | (4S)-3-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid |
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| Synonym | More Synonyms |
| Description | Imidapril (TA-6366 free base) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research[1][2]. |
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| Related Catalog | |
| Target |
MMP-9 |
| References |
| Density | 1.266 g/cm3 |
|---|---|
| Boiling Point | 577ºC at 760 mmHg |
| Melting Point | 195-197°C |
| Molecular Formula | C20H27N3O6 |
| Molecular Weight | 405.44500 |
| Flash Point | 302.8ºC |
| Exact Mass | 405.19000 |
| PSA | 116.25000 |
| LogP | 1.14290 |
| Storage condition | -20°C Freezer |
| Risk Phrases | R22:Harmful if swallowed. R34:Causes burns. |
|---|---|
| Safety Phrases | S26-S36/37/39 |
| RIDADR | 1759 |
| Packaging Group | II |
| Hazard Class | 8 |
|
~94%
Imidapril CAS#:89371-37-9 |
| Literature: US4508727 A1, ; US 4508727 A |
|
~%
Imidapril CAS#:89371-37-9 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 39, # 6 p. 1374 - 1377 |
![benzyl (4S)-3-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylate structure](https://image.chemsrc.com/caspic/123/89371-36-8.png)
| Precursor 0 | |
|---|---|
| DownStream 2 | |
CAS#:64-17-5
CAS#:89371-44-8| imidapril |
| (4S)-3-<(2S)-2-<N-<(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl>amino>propionyl>-1-methyl-2-oxoimidazolidine-4-carboxylic Acid |
| Hipertene (TN) |
| Imidapril [BAN:INN] |
| Imidaprilum |
| (S)-3-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid |
| Imidapril HCl |
| (4S)-1-methyl-3-{(2S)-2-[N-(1S)-1-ethoxycarbonyl-3-phenylpropyl)amino]propionyl}-2-oxoimidazolidine-4-carboxylic acid |
| Imidapril (INN) |
| Imidaprilum [INN-Latin] |
| MFCD00870777 |