HO-PEG21-OH

Modify Date: 2024-01-05 10:43:01

HO-PEG21-OH Structure
HO-PEG21-OH structure
Common Name HO-PEG21-OH
CAS Number 928211-42-1 Molecular Weight 943.12
Density N/A Boiling Point N/A
Molecular Formula C42H86O22 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HO-PEG21-OH


HO-PEG21-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG22
Synonym More Synonyms

 HO-PEG21-OH Biological Activity

Description HO-PEG21-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C42H86O22
Molecular Weight 943.12

 Synonyms

MFCD29079392
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