BnO-PEG1-CH2COOH
BnO-PEG1-CH2COOH structure
|
Common Name | BnO-PEG1-CH2COOH | ||
|---|---|---|---|---|
| CAS Number | 93206-09-8 | Molecular Weight | 210.22600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H14O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BnO-PEG1-CH2COOHBnO-PEG1-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
| Name | 2-(2-phenylmethoxyethoxy)acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | BnO-PEG1-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Molecular Formula | C11H14O4 |
|---|---|
| Molecular Weight | 210.22600 |
| Exact Mass | 210.08900 |
| PSA | 55.76000 |
| LogP | 1.30440 |
|
~93%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: ARISGEN SA; BOTTI, Paolo; TCHERTCHIAN, Sylvie; THEURILLAT, Doriane Patent: WO2011/64300 A1, 2011 ; Location in patent: Page/Page column 37 ; |
|
~95%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: NYCOMED GMBH; BARTELS, Bjoern; WEINBRENNER, Steffen; MARX, Degenhard; DIEFENBACH, Joerg; DUNKERN, Torsten; MENGE, Wiro M.P.B.; CHRISTIAANS, Johannes A. M. Patent: WO2010/15588 A1, 2010 ; Location in patent: Page/Page column 98 ; WO 2010/015588 A1 |
|
~%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: Tanabe Seiyaku Co., Ltd. Patent: EP1489078 A1, 2004 ; Location in patent: Page 191 ; EP 1489078 A1 |
|
~92%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: Ng, Pei-Sze; Laing, Brian M.; Balasundarum, Ganesan; Pingle, Maneesh; Friedman, Alan; Bergstrom, Donald E. Bioconjugate Chemistry, 2010 , vol. 21, # 8 p. 1545 - 1553 |
|
~%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: Ashton, Peter R.; Hoerner, Bernd; Kocian, Oldrich; Menzer, Stephan; White, Andrew J. P.; Stoddart, J. Fraser; Williams, David J. Synthesis, 1996 , # 8 p. 930 - 940 |
|
~71%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: Mitchell; Hill; Newton; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 697 - 699 |
|
~%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: ArisGen SA Patent: EP2332929 A1, 2011 ; |
|
~%
BnO-PEG1-CH2COOH CAS#:93206-09-8 |
| Literature: Foley, David; Pieri, Myrtani; Pettecrew, Rachel; Price, Richard; Miles, Stephen; Lam, Ho Kam; Bailey, Patrick; Meredith, David Organic and Biomolecular Chemistry, 2009 , vol. 7, # 18 p. 3652 - 3656 |
| 7-phenyl-3,6-dioxaheptanoic acid |