Chloroacetamido-C-PEG3-C3-NHBoc

Modify Date: 2024-01-09 10:19:49

Chloroacetamido-C-PEG3-C3-NHBoc Structure
Chloroacetamido-C-PEG3-C3-NHBoc structure
Common Name Chloroacetamido-C-PEG3-C3-NHBoc
CAS Number 934164-55-3 Molecular Weight 396.91
Density N/A Boiling Point N/A
Molecular Formula C17H33ClN2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Chloroacetamido-C-PEG3-C3-NHBoc


Chloroacetamido-C-PEG3-C3-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Chloroacetamido-C-PEG3-C3-NHBoc

 Chloroacetamido-C-PEG3-C3-NHBoc Biological Activity

Description Chloroacetamido-C-PEG3-C3-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H33ClN2O6
Molecular Weight 396.91