TCS HDAC6 20b

Modify Date: 2024-01-12 19:04:33

TCS HDAC6 20b Structure
TCS HDAC6 20b structure
Common Name TCS HDAC6 20b
CAS Number 956154-63-5 Molecular Weight 480.704
Density 1.1±0.1 g/cm3 Boiling Point 631.3±55.0 °C at 760 mmHg
Molecular Formula C26H44N2O4S Melting Point N/A
MSDS N/A Flash Point 335.6±31.5 °C

 Use of TCS HDAC6 20b


TCS HDAC6 20b is a HDAC6-selective inhibitor. TCS HDAC6 20b blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells[1].

 Names

Name S-[(6S)-7-(Adamantan-1-ylamino)-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-7-oxoheptyl] 2-methylpropanethioate
Synonym More Synonyms

 TCS HDAC6 20b Biological Activity

Description TCS HDAC6 20b is a HDAC6-selective inhibitor. TCS HDAC6 20b blocks the growth of estrogen receptor α-positive breast cancer MCF-7 cells[1].
Related Catalog
References

[1]. Yukihiro Itoh, et al. Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem. 2007 Nov 1;50(22):5425-38.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 631.3±55.0 °C at 760 mmHg
Molecular Formula C26H44N2O4S
Molecular Weight 480.704
Flash Point 335.6±31.5 °C
Exact Mass 480.302185
LogP 5.66
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.537

 Synonyms

Propanethioic acid, 2-methyl-, S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester
S-[(6S)-7-(Adamantan-1-ylamino)-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-7-oxoheptyl] 2-methylpropanethioate
S-[(6S)-6-[(tert-butoxycarbonyl)amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] 2-methylpropanethioate
TCS HDAC6 20b
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