3',5'-Di-O-benzoyl fialuridine

Modify Date: 2024-01-10 07:09:45

3',5'-Di-O-benzoyl fialuridine Structure
3',5'-Di-O-benzoyl fialuridine structure
Common Name 3',5'-Di-O-benzoyl fialuridine
CAS Number 97614-45-4 Molecular Weight 580.30
Density N/A Boiling Point N/A
Molecular Formula C23H18FIN2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3',5'-Di-O-benzoyl fialuridine


3',5'-Di-O-benzoyl fialuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name [(2R,4R,5R)-3-benzoyloxy-4-fluoro-5-(5-iodo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl benzoate
Synonym More Synonyms

 3',5'-Di-O-benzoyl fialuridine Biological Activity

Description 3',5'-Di-O-benzoyl fialuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C23H18FIN2O7
Molecular Weight 580.30
Exact Mass 580.01400
PSA 116.95000
LogP 2.87160

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

3',5'-Di-O-benzoyl Fialuridine
3 inverted exclamation mark,5 inverted exclamation mark-Di-O-benzoyl-1-(2-deoxy-2-fluoro-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione
3 inverted exclamation mark,5 inverted exclamation mark-Di-O-benzoyl-1-(2'-deoxy-2'-fluoro-D-arabinofuranosyl)-5-iodouracil