A1AR antagonist 3

Modify Date: 2024-04-06 12:35:24

A1AR antagonist 3 Structure
A1AR antagonist 3 structure
Common Name A1AR antagonist 3
CAS Number 2413257-73-3 Molecular Weight 428.50
Density N/A Boiling Point N/A
Molecular Formula C25H20N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A1AR antagonist 3


A1AR antagonist 3 (compound 13) is a selective adenosine 1 (A1) receptor antagonist with Kis of 9.69 nM and 0.529 nM for human A1 and rat A1, respectively. A1AR antagonist 3 can be used for researching neurological diseases[1].

 Names

Name A1AR antagonist 3

 A1AR antagonist 3 Biological Activity

Description A1AR antagonist 3 (compound 13) is a selective adenosine 1 (A1) receptor antagonist with Kis of 9.69 nM and 0.529 nM for human A1 and rat A1, respectively. A1AR antagonist 3 can be used for researching neurological diseases[1].
Related Catalog
Target

human A1:9.69 nM (Ki)

rat A1:0.529 nM (Ki)

References

[1]. Abdelrahman A, et al. Substituted 4-phenylthiazoles: Development of potent and selective A1, A3 and dual A1/A3 adenosine receptor antagonists. Eur J Med Chem. 2020;186:111879.

 Chemical & Physical Properties

Molecular Formula C25H20N2O3S
Molecular Weight 428.50