A3AR antagonist 1

Modify Date: 2024-01-07 13:02:54

A3AR antagonist 1 structure	Common Name	A3AR antagonist 1
	CAS Number	2413257-74-4	Molecular Weight	560.62
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₂₄N₄O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of A3AR antagonist 1

A3AR antagonist 1 (compound 17) is a potent and selective human A3 adenosine receptor (AR) antagonist, with an Ki of 4.63 nM. A3AR antagonist 1 shows no affinity for the rat A3 AR even at high concentrations[1].

Name	A3AR antagonist 1

Description	A3AR antagonist 1 (compound 17) is a potent and selective human A3 adenosine receptor (AR) antagonist, with an Ki of 4.63 nM. A3AR antagonist 1 shows no affinity for the rat A3 AR even at high concentrations[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	hA3:4.63 nM (Ki)
References	[1]. Abdelrahman A, et, al. Substituted 4-phenylthiazoles: Development of potent and selective A 1, A 3 and dual A 1/A 3 adenosine receptor antagonists. Eur J Med Chem. 2020 Jan 15;186:111879.

Molecular Formula	C₃₂H₂₄N₄O₄S
Molecular Weight	560.62