VEGFR-2-IN-26

Modify Date: 2024-01-02 19:53:26

VEGFR-2-IN-26 structure	Common Name	VEGFR-2-IN-26
	CAS Number	2439096-06-5	Molecular Weight	480.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₁₉F₃N₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VEGFR-2-IN-26

VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells[1].

Name	VEGFR-2-IN-26

Description	VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR-2:15.5 nM (IC50)
References	[1]. Hadi SRAE, et al. Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors. Bioorg Chem. 2020 Aug;101:103961.

Molecular Formula	C₂₄H₁₉F₃N₆O₂
Molecular Weight	480.44

VEGFR-2-IN-26

Use of VEGFR-2-IN-26

Names

VEGFR-2-IN-26 Biological Activity

Chemical & Physical Properties