Apoptotic agent-1

Modify Date: 2024-01-15 19:34:48

Apoptotic agent-1 structure	Common Name	Apoptotic agent-1
	CAS Number	2490538-26-4	Molecular Weight	319.73
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₆ClN₅O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Apoptotic agent-1

Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].

Name	Apoptotic agent-1

Description	Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Apoptotic agent-1 (Compound 8a) shows antiproliferative activity with IC50 values of 53.3, 12.9 and > 100 µM against HepG2, MCF-7 and WI-38 cells, respectively[1].
References	[1]. Haffez H, et al. Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity. Bioorg Chem. 2020 Nov;104:104249.

Molecular Formula	C₁₂H₆ClN₅O₂S
Molecular Weight	319.73