Topoisomerase II inhibitor 8

Modify Date: 2024-01-12 12:37:45

Topoisomerase II inhibitor 8 structure	Common Name	Topoisomerase II inhibitor 8
	CAS Number	2493298-68-1	Molecular Weight	312.30
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₈N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Topoisomerase II inhibitor 8

Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].

Name	Topoisomerase II inhibitor 8

Description	Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	Topoisomerase II:0.52 μM (IC50)
References	[1]. Abbass EM, et, al. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers. Bioorg Chem. 2020 Nov;104:104255.

Molecular Formula	C₁₄H₈N₄O₃S
Molecular Weight	312.30

Topoisomerase II inhibitor 8

Use of Topoisomerase II inhibitor 8

Names

Topoisomerase II inhibitor 8 Biological Activity

Chemical & Physical Properties