Antiproliferative agent-7

Modify Date: 2024-01-13 18:47:08

Antiproliferative agent-7 Structure
Antiproliferative agent-7 structure
Common Name Antiproliferative agent-7
CAS Number 2497687-47-3 Molecular Weight 440.58
Density N/A Boiling Point N/A
Molecular Formula C28H32N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiproliferative agent-7


Antiproliferative against-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative against-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative against-7 can increase ROS production and induce apoptosis[1].

 Names

Name Antiproliferative agent-7

 Antiproliferative agent-7 Biological Activity

Description Antiproliferative against-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative against-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative against-7 can increase ROS production and induce apoptosis[1].
Related Catalog
Target

IC50: 3.5 μM (MCF-7), 15.54 μM (MDA-MB-231), 30.43 μM (HCT-116), 34.8 μM (FR-2)[1]

References

[1]. Dheer D,et al.Design, synthesis and comparative analysis of triphenyl-1,2,3-triazoles as anti-proliferative agents. Eur J Med Chem. 2020 Dec 1;207:112813.

 Chemical & Physical Properties

Molecular Formula C28H32N4O
Molecular Weight 440.58