PI3K-IN-28

Modify Date: 2024-01-10 18:52:44

PI3K-IN-28 structure	Common Name	PI3K-IN-28
	CAS Number	2747100-02-1	Molecular Weight	653.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₁₆F₉N₃O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PI3K-IN-28

PI3K-IN-28 (Compound 6c) is a potent inhibitor of PI3K. PI3K-IN-28 displays the most potent activity with lower toxic effects on MCF-10a. PI3K-IN-28 displays half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. PI3K-IN-28 is the most potent one with a selectivity index (SI) of 39 and is considered as a latent lead for further optimization of anticancer agents[1].

Name	PI3K-IN-28

Description	PI3K-IN-28 (Compound 6c) is a potent inhibitor of PI3K. PI3K-IN-28 displays the most potent activity with lower toxic effects on MCF-10a. PI3K-IN-28 displays half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. PI3K-IN-28 is the most potent one with a selectivity index (SI) of 39 and is considered as a latent lead for further optimization of anticancer agents[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
References	[1]. Tantawy AH, et al. Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Fluorinated Candidates as PI3K Inhibitors: Targeting Fluorophilic Binding Sites. J Med Chem. 2021 Dec 9;64(23):17468-17485.

Molecular Formula	C₂₆H₁₆F₉N₃O₃S₂
Molecular Weight	653.54

PI3K-IN-28

Use of PI3K-IN-28

Names

PI3K-IN-28 Biological Activity

Chemical & Physical Properties