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丁二酸钠

丁二酸钠用途

Disodium succinate 是 Succinic acid 的盐形式。Succinic acid 是三羧酸循环的中间产物,也是无氧代谢的发酵产物之一。

丁二酸钠名称

[ CAS 号 ]:
150-90-3

[ 中文名 ]:
丁二酸二钠

[ 英文名 ]:
Disodium succinate

[中文别名 ]:

[英文别名 ]:

sodium succinate
Sodium succinate dibasic
Succinic acid disodium salt
sodium 21-succinate
succinic acid sodium salt
EINECS 205-778-7
Diflufenzopyr
Succinic acid, disodium salt
UNII-V8ZGC8ISR3
Disodium succinate

丁二酸钠生物活性

[ 描述 ]:

Disodium succinate 是 Succinic acid 的盐形式。Succinic acid 是三羧酸循环的中间产物,也是无氧代谢的发酵产物之一。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10.

丁二酸钠物理化学性质

[ 分子式 ]:
C₄H₄Na₂O₄

[ 分子量 ]:
162.052

[ 闪点 ]:
110.9ºC

[ 精确质量 ]:
161.990494

[ PSA ]:
80.26000

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0165mmHg at 25°C

[ 储存条件 ]:
室温

[ 水溶解性 ]:
300 g/L (25 ºC)

丁二酸钠MSDS

丁二酸钠毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WM7751000

CHEMICAL NAME :: Succinic acid, disodium salt

CAS REGISTRY NUMBER :: 150-90-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-H4-O4.2Na

MOLECULAR WEIGHT :: 162.06

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,1368,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80528 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80528 No. of Facilities: 159 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 2247 (estimated) No. of Female Employees: 1382 (estimated)

丁二酸钠安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
WM7751000

[ 海关编码 ]:
2917190090

丁二酸钠合成路线

丁二酸钠上下游产品

丁二酸钠上游产品

丁二酸钠下游产品

丁二酸钠制备

将琥珀酸与氢氧化钠中和，经120℃干燥、粉碎即可。

丁二酸钠海关

[ 海关编码 ]: 2917190090

[ 中文概述 ]:
2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

丁二酸钠文献

Oxidative damage of rat liver mitochondria during exposure to t-butyl hydroperoxide. Role of Ca²⁺ ions in oxidative processes.

Life Sci. 92(23) , 1110-7, (2013)

The present study was designed for further evaluation of the biochemical mechanism of hepatic mitochondrial dysfunction under oxidative damages induced by organic hydroperoxide, tert-butyl hydroperoxi...

Toxicity of copper on isolated liver mitochondria: impairment at complexes I, II, and IV leads to increased ROS production.

Cell Biochem. Biophys. 70(1) , 367-81, (2014)

Oxidative damage has been implicated in disorders associated with abnormal copper metabolism and also Cu(2+) overloading states. Besides, mitochondria are one of the most important targets for Cu(2+),...

Phenotype consequences of myophosphorylase dysfunction: insights from the McArdle mouse model.

J. Physiol. 593 , 2693-706, (2015)

This is the first study to analyse the effect of muscle glycogen phosphorylase depletion in metabolically different muscle types. In McArdle mice, muscle glycogen phosphorylase is absent in both oxida...

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