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N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯用途

Boc-Glu OBzl是一种谷氨酸衍生物[1]。

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯名称

[ CAS 号 ]:
30924-93-7

[ 中文名 ]:
N-叔丁氧羰基-L-谷氨酸 1-苄酯

[ 英文名 ]:
Boc-L-glutamic acid 1-benzyl ester

[中文别名 ]:

[英文别名 ]:

N-α-tert-BOC-L-glutamic-γ-benzyl ester
Boc-L-glutamic acid 1-benzyl ester
Boc-Glu-OBzl
5-Benzyl N-(tert-Butoxycarbonyl)-L-glutamate
Boc-L-glutamic acid 5-benzyl ester
5-Benzyl N-Boc-L-glutamate
MFCD00065568
N-t-butoxycarbonyl-L-glutamic acid benzyl ester
B-Glu-BE
Boc-(S)-glutamic acid benzyl ester

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯生物活性

[ 描述 ]:

Boc-Glu OBzl是一种谷氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
522.6±50.0 °C at 760 mmHg

[ 熔点 ]:
97 °C

[ 分子式 ]:
C₁₇H₂₃NO₆

[ 分子量 ]:
337.368

[ 闪点 ]:
269.9±30.1 °C

[ 精确质量 ]:
337.152527

[ PSA ]:
101.93000

[ LogP ]:
3.34

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.524

[ 储存条件 ]:
−20°C

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯MSDS

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2924299090

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯合成路线

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯上下游产品

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯上游产品

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯下游产品

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯文献

Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter.

Eur. J. Pharm. Sci. 11 , 43-50, (2000)

One approach to increase drug stability and to facilitate oral absorption of low bioavailability drugs may be to design oligopeptide ester prodrugs which are stable in the gastrointestinal tract, are ...

Side reactions in solid-phase peptide synthesis and their applications.

Int. J. Pept. Protein Res. 48 , 292-298, (1996)

Side reactions in peptide synthesis indicate steps needing improvement as well as opportunities for structural diversification in combinatorial design. Among the side reactions observed in this study,...

Modification of the vitamin K-dependent carboxylase assay.

J. Biochem. Biophys. Methods 11 , 59, (1985)

Methods are presented that describe alternative protocols for the isolation of rat liver microsomes containing the vitamin K-dependent carboxylase and the procedure in which the solubilized enzyme is ...

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