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芦荟宁

芦荟宁用途

Aloenin (Aloenin A) 是一类从芦荟中分离出的蒽醌类。Aloenin 具有有效的清除过氧自由基的活性,对 β-分泌酶 (BACE) 具有中等抑制活性。

芦荟宁名称

[ CAS 号 ]:
38412-46-3

[ 中文名 ]:
芦荟宁

[ 英文名 ]:
aloenin a

[中文别名 ]:

芦荟宁

[英文别名 ]:

Aloenin A
Aloenin

芦荟宁生物活性

[ 描述 ]:

Aloenin (Aloenin A) 是一类从芦荟中分离出的蒽醌类。Aloenin 具有有效的清除过氧自由基的活性,对 β-分泌酶 (BACE) 具有中等抑制活性。

[ 相关类别 ]:

信号通路 >> 神经信号通路 >> β-分泌

研究领域 >> 神经疾病

[参考文献]

[1]. Sun YN, et al. Antioxidant and anti-osteoporotic effects of anthraquinones and related constituents from the aqueous dissolved Aloe exudates. Nat Prod Res. 2017 Dec;31(23):2810-2813.

[2]. Gao B, et al. Active constituents from Aloe arborescens as BACE inhibitors. Yao Xue Xue Bao. 2006 Oct;41(10):1000-3.

芦荟宁物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
787.8±60.0 °C at 760 mmHg

[ 熔点 ]:
145℃

[ 分子式 ]:
C₁₉H₂₂O₁₀

[ 分子量 ]:
410.372

[ 闪点 ]:
282.2±26.4 °C

[ 精确质量 ]:
410.121307

[ PSA ]:
159.05000

[ LogP ]:
-0.48

[ 蒸汽压 ]:
0.0±2.9 mmHg at 25°C

[ 折射率 ]:
1.663

[ 储存条件 ]:
?20°C

芦荟宁MSDS

详细MSDS(安全技术说明书)

芦荟宁安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

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芦荟宁文献

The content of secondary phenol metabolites in pruned leaves of Aloe arborescens, a comparison between two methods: leaf exudates and leaf water extract.

J. Nat. Med. 62(4) , 430-5, (2008)

Aloe arborescens plants, originating from the deserts of South Africa, are grown in the Introduction Garden at Sede Boker in the Negev Desert of Israel. In previous studies, we developed agro-technica...

Determination of aloenin, barbaloin and isobarbaloin in aloe species by micellar electrokinetic chromatography.

J. Chromatogr. B. Biomed. Sci. Appl. 752(1) , 91-7, (2001)

Aloenin, barbaloin and isobarbaloin in JP Aloe, Aloe barbadensis (Aloe vera) and Aloe arborescens Miller var. natalensis Berger (Aloe arborescens Miller) were determined by micellar electrokinetic chr...

Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components.

J. Ethnopharmacol. 103(3) , 468-77, (2006)

We carried out three experimental trials to determine antidiabetic effects of Aloe arborescens Miller components. Firstly, ICR mice which received frequent injections of streptozotocin (Sz) in small d...

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芦荟宁