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桑色素

桑色素用途

Morin 是一种植物性黄酮类化合物,具有较低的抗氧化活性。Morin 是一种用于铝物种形成的荧光螯合剂。

桑色素名称

[ CAS 号 ]:
480-16-0

[ 中文名 ]:
桑色素

[ 英文名 ]:
Morin

[中文别名 ]:

[英文别名 ]:

Aluminum Ionophore I
Aurantica
Morin
Morin hydrate
EINECS 207-542-9
MFCD00006826
2',3,4',5,7-Pentahydroxyflavone
Bois d'Arc
Calico Yellow
Al-Morin

桑色素生物活性

[ 描述 ]:

Morin 是一种植物性黄酮类化合物,具有较低的抗氧化活性。Morin 是一种用于铝物种形成的荧光螯合剂。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Duthie G, et al. Antioxidant capacity of flavonoids in hepatic microsomes is not reflected by antioxidant effects in vivo. Oxid Med Cell Longev. 2012;2012:165127.

[2]. Lian HZ, et al. Morin applied in speciation of aluminium in natural waters and biological samples by reversed-phase high-performance liquid chromatography with fluorescence detection. Anal Bioanal Chem. 2003 Jun;376(4):542-8. Epub 2003 May 9.

桑色素物理化学性质

[ 密度 ]:
1.8±0.1 g/cm3

[ 沸点 ]:
645.5±55.0 °C at 760 mmHg

[ 熔点 ]:
299-300 °C (dec.)(lit.)

[ 分子式 ]:
C₁₅H₁₀O₇

[ 分子量 ]:
302.236

[ 闪点 ]:
249.3±25.0 °C

[ 精确质量 ]:
302.042664

[ PSA ]:
131.36000

[ LogP ]:
1.61

[ 外观性状 ]:
黄色至棕色粉末

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.823

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
methanol: 50 mg/mL

桑色素MSDS

桑色素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LK8749000

CHEMICAL NAME :: Flavone, 2',3,4',5,7-pentahydroxy-

CAS REGISTRY NUMBER :: 480-16-0

BEILSTEIN REFERENCE NO. :: 0327474

LAST UPDATED :: 199801

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H10-O7

MOLECULAR WEIGHT :: 302.25

WISWESSER LINE NOTATION :: T66 BO EVJ CR BQ DQ& DQ GQ IQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 555 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 10 umol/L

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 35,443,1997

桑色素安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ WGK德国 ]:
3

[ RTECS号 ]:
LK8749000

桑色素合成路线

桑色素上下游产品

桑色素上游产品

桑色素下游产品

桑色素制备

黄木树的根或木质部分用乙醇浸泡提取后，再经精制而得。

桑色素文献

The toxicity of NaF on BmN cells and a comparative proteomics approach to identify protein expression changes in cells under NaF-stress: impact of NaF on BmN cells.

J. Hazard. Mater. 286 , 624-31, (2015)

Fluorides negatively affect the development of organisms and are a threat to human health and environmental safety. In this study, Bombyx mori N cell line (BmN) were used to explore effects of NaF on ...

In vitro effects of myricetin, morin, apigenin, (+)-taxifolin, (+)-catechin, (-)-epicatechin, naringenin and naringin on cytochrome b5 reduction by purified NADH-cytochrome b5 reductase.

Toxicology 308 , 34-40, (2013)

The microsomal NADH-dependent electron transport system consisting of cytochrome b5 reductase and cytochrome b5 participates in a number of physiologically important processes including lipid metaboli...

Enhanced oral bioavailability of morin administered in mixed micelle formulation with PluronicF127 and Tween80 in rats.

Biol. Pharm. Bull. 38(2) , 208-17, (2015)

To overcome the low oral bioavailability of morin, a mixed micelle formulation with pharmaceutical excipients that facilitate solubilization and modulate P-glycoprotein (P-gp) was developed and evalua...

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桑色素