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D(+)-无水葡萄糖

D(+)-无水葡萄糖用途

Dextrose(D-glucose)是重要的单糖。

D(+)-无水葡萄糖名称

[ CAS 号 ]:
50-99-7

[ 中文名 ]:
D-(+)-葡萄糖

[ 英文名 ]:
D-(+)-Glucose

[中文别名 ]:

[英文别名 ]:

D-(+)-Glucose,Dextrose
D-Glucose
D(+)-Glucose
EINECS 200-075-1
MFCD00063684
D-(+)-Glucose
D-(+)-Dextrose
aldehydo-D-glucose
(2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal
Glucose

D(+)-无水葡萄糖生物活性

[ 描述 ]:

Dextrose(D-glucose)是重要的单糖。

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 糖和糖苷

[ 靶点 ]

Human Endogenous Metabolite

[相关活性小分子]

D(+)-无水葡萄糖物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
527.1±50.0 °C at 760 mmHg

[ 熔点 ]:
146 ºC

[ 分子式 ]:
C₆H₁₂O₆

[ 分子量 ]:
180.156

[ 闪点 ]:
286.7±26.6 °C

[ 精确质量 ]:
180.063385

[ PSA ]:
118.22000

[ LogP ]:
-3.17

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±3.1 mmHg at 25°C

[ 折射率 ]:
1.573

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

[ 水溶解性 ]:
Soluble

D(+)-无水葡萄糖MSDS

详细MSDS(安全技术说明书)

D(+)-无水葡萄糖毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ6600000

CHEMICAL NAME :: D-Glucose

CAS REGISTRY NUMBER :: 50-99-7

BEILSTEIN REFERENCE NO. :: 1724615

LAST UPDATED :: 199710

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: C6-H12-O6

MOLECULAR WEIGHT :: 180.18

WISWESSER LINE NOTATION :: T6OTJ BQ CQ DQ EQ F1Q -D,GLU

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25800 mg/kg

TOXIC EFFECTS :: Behavioral - coma Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15400 gm/kg/22W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2 gm/kg

SEX/DURATION :: female 28 week(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 2 gm/kg

SEX/DURATION :: female 39 week(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - other effects to embryo

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 1057 ug/kg

SEX/DURATION :: female 39 week(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - hepatobiliary system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 1300 mg/kg

SEX/DURATION :: female 39 week(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 300 gm/kg

SEX/DURATION :: female 30 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 20 gm/kg

SEX/DURATION :: female 6-8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 20 gm/kg

SEX/DURATION :: female 6-8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Multiple routes

DOSE :: 20 gm/kg

SEX/DURATION :: female 6-8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Multiple routes

DOSE :: 20 mg/kg

SEX/DURATION :: female 6-8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - urogenital system

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 179 mmol/L

REFERENCE :: MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81836 No. of Facilities: 16738 (estimated) No. of Industries: 117 No. of Occupations: 90 No. of Employees: 136870 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81836 No. of Facilities: 11017 (estimated) No. of Industries: 86 No. of Occupations: 102 No. of Employees: 363666 (estimated) No. of Female Employees: 186490 (estimated)

D(+)-无水葡萄糖安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
LZ6600000

[ 海关编码 ]:
2940000000

D(+)-无水葡萄糖上下游产品

D(+)-无水葡萄糖上游产品

D(+)-无水葡萄糖下游产品

D(+)-无水葡萄糖制备

1.葡萄糖是自然界中存在量最大的化合物之一，是光合作用的产物。它以游离的形式存在于植物的浆汁中，尤其是在水果、蜂蜜、血浆、淋巴液中。正常人血液中的葡萄糖含量为0.08%-0.1%，而更大量的存在形式是结合组成蔗糖、淀粉、肝糖、纤维素和苷等。最初葡萄糖是从葡萄汁中分离结晶得到的，并因此而得名。工业生产葡萄糖是通过淀粉水解制得，过去用稀盐酸水解淀粉，现在几乎完全由酶水解代替稀盐酸。

2.淀粉水解可得葡萄糖。

D(+)-无水葡萄糖海关

[ 海关编码 ]: 2912491000

[ 中文概述 ]:
2912491000. 醛醇. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ Summary ]:
2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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