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DL-3-苯基-2-羟丙酸

DL-3-苯基-2-羟丙酸用途

DL-3-Phenyllactic acid 是一种广谱抗菌化合物。

DL-3-苯基-2-羟丙酸名称

[ CAS 号 ]:
828-01-3

[ 中文名 ]:
DL-3-苯基-2-羟丙酸

[ 英文名 ]:
D-3-phenyllactic acid

[中文别名 ]:

[英文别名 ]:

(R)-2-hydroxy-3-phenylpropionic acid
α-Hydroxybenzenepropanoic acid
DL-3-Phenyllactic acid
DL-β-Phenylacetic acid
DL-2-Hydroxy-3-phenylpropionate
(R)-b-Phenyllactic acid
2-Hydroxy-3-phenylpropionic acid
a-Hydroxybenzenepropanoic acid
(2R)-2-Hydroxy-3-phenylpropanoic acid
b-Phenyllactic acid

DL-3-苯基-2-羟丙酸生物活性

[ 描述 ]:

DL-3-Phenyllactic acid 是一种广谱抗菌化合物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

天然产物 >> 酸和醛

研究领域 >> 感染

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

DL-3-苯基乳酸(3-苯基乳酸,PLA)是一种广泛存在于蜂蜜和乳酸菌发酵食品中的有机酸,可以由许多微生物,特别是乳酸菌生产。 DL-3-苯基乳酸被证明是一种理想的抗菌化合物,对细菌和真菌具有广泛而有效的抗菌活性。此外,DL-3-苯基乳酸可用作饲料添加剂,以替代牲畜饲料中的抗生素[1]。

[参考文献]

[1]. Mu W, et al. Recent research on 3-phenyllactic acid, a broad-spectrum antimicrobial compound. Appl Microbiol Biotechnol. 2012 Sep;95(5):1155-63.

[相关活性小分子]

DL-3-苯基-2-羟丙酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
331.6±22.0 °C at 760 mmHg

[ 熔点 ]:
95-98 °C

[ 分子式 ]:
C₉H₁₀O₃

[ 分子量 ]:
166.174

[ 闪点 ]:
168.5±18.8 °C

[ 精确质量 ]:
166.062988

[ PSA ]:
57.53000

[ LogP ]:
1.05

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.577

[ 储存条件 ]:
2-8°C

DL-3-苯基-2-羟丙酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2918199090

DL-3-苯基-2-羟丙酸合成路线

详细合成路线

DL-3-苯基-2-羟丙酸上下游产品

DL-3-苯基-2-羟丙酸上游产品

DL-3-苯基-2-羟丙酸下游产品

DL-3-苯基-2-羟丙酸制备

1. 烟草：OR，41；BU，26。

DL-3-苯基-2-羟丙酸海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

DL-3-苯基-2-羟丙酸文献

In vitro antibacterial phenolic extracts from "sugarbag" pot-honeys of Australian stingless bees (Tetragonula carbonaria).

J. Agric. Food Chem. 62(50) , 12209-17, (2014)

Australian stingless bee honeys have been shown to exert antioxidant and in vitro antimicrobial properties; however their bioactive factors remained unidentified. This study investigated the antibacte...

Recent research on 3-phenyllactic acid, a broad-spectrum antimicrobial compound.

Appl. Microbiol. Biotechnol. 95(5) , 1155-63, (2012)

3-Phenyllactic acid (PLA), which is an organic acid widely existing in honey and lactic acid bacteria fermented food, can be produced by many microorganisms, especially lactic acid bacteria. It was pr...

Insight into microwave irradiation and enzyme catalysis in enantioselective resolution of DL-(±)-3-phenyllactic acid.

Appl. Microbiol. Biotechnol. 96(1) , 69-79, (2012)

Lipase catalyzed kinetic resolution of DL-(±)-3-phenyllactic acid (DL-(±)-3-PLA) was investigated to study the synergistic effect of microwave irradiation and enzyme catalysis. Lipases from different ...

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