<生产厂家价格>

2-甲氧基-4-甲基苯酚

2-甲氧基-4-甲基苯酚用途

Creosol 是一种内源性代谢产物。

2-甲氧基-4-甲基苯酚名称

[ CAS 号 ]:
93-51-6

[ 中文名 ]:
2-甲氧基-4-甲基苯酚

[ 英文名 ]:
Creosol

[中文别名 ]:

[英文别名 ]:

Homoguaiacol
p-Cresol,2-methoxy
creosol
2-methoxy-4-cresol
2-Methoxy-p-cresol
EINECS 202-252-9
p-Methylguaiacol
p-Creosol
4-Methylguaiacol
3-methoxy-4-hydroxytoluene

2-甲氧基-4-甲基苯酚生物活性

[ 描述 ]:

Creosol 是一种内源性代谢产物。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

2-甲氧基-4-甲基苯酚物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
220.0±0.0 °C at 760 mmHg

[ 熔点 ]:
5 °C(lit.)

[ 分子式 ]:
C₈H₁₀O₂

[ 分子量 ]:
138.164

[ 闪点 ]:
99.4±0.0 °C

[ 精确质量 ]:
138.068085

[ PSA ]:
29.46000

[ LogP ]:
1.65

[ 外观性状 ]:
透明液体

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.531

[ 储存条件 ]:
室温

2-甲氧基-4-甲基苯酚MSDS

2-甲氧基-4-甲基苯酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GP1755000

CHEMICAL NAME :: p-Cresol, 2-methoxy-

CAS REGISTRY NUMBER :: 93-51-6

BEILSTEIN REFERENCE NO. :: 1862340

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C8-H10-O2

MOLECULAR WEIGHT :: 138.18

WISWESSER LINE NOTATION :: QR D1 BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 740 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 76 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30196 mg/kg/40D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 500 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1512 No. of Facilities: 14 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 1639 (estimated) No. of Female Employees: 276 (estimated)

2-甲氧基-4-甲基苯酚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S24/25

[ 危险品运输编码 ]:
2810

[ WGK德国 ]:
3

[ RTECS号 ]:
GP1755000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

[ 海关编码 ]:
29095090

2-甲氧基-4-甲基苯酚合成路线

2-甲氧基-4-甲基苯酚上下游产品

2-甲氧基-4-甲基苯酚上游产品

2-甲氧基-4-甲基苯酚下游产品

2-甲氧基-4-甲基苯酚制备

1.天然可从桦皮焦油、杂酚油、木馏油等用碱处理，抽提后，分馏得到。

2. 烟草：OR，26。

2-甲氧基-4-甲基苯酚海关

[ 海关编码 ]: 2909500000

[ 中文概述 ]:
2909500000. 醚酚、醚醇酚及其卤化、磺化、硝化或亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

2-甲氧基-4-甲基苯酚文献

In chemico evaluation of prohapten skin sensitizers: behavior of 2-methoxy-4-(¹³C)methylphenol in the peroxidase peptide reactivity assay (PPRA) as an alternative to animal testing.

Toxicol. Lett. 218(3) , 266-72, (2013)

In chemico methods, based on the assessment of a hapten's reactivity toward peptides, have been proposed as alternative methods for the assessment of the skin sensitizing potential of chemicals. Howev...

Rapid discrimination and characterization of vanilla bean extracts by attenuated total reflection infrared spectroscopy and selected ion flow tube mass spectrometry.

J. Food Sci. 77(3) , C284-92, (2012)

Vanilla beans have been shown to contain over 200 compounds, which can vary in concentration depending on the region where the beans are harvested. Several compounds including vanillin, p-hydroxybenza...

Binding of alkyl- and alkoxy-substituted simple phenolic compounds to human serum proteins.

Res. Commun. Mol. Pathol. Pharmacol. 107(1-2) , 167-73, (2000)

Wood creosote, primarily a mixture of simple alkyl- and/or alkoxy-substituted phenolic compounds with closely related structures, has long been used as an oral antidiarrheal agent. The use of wood cre...

更多文献