850-52-2

• 常用中文名：烯丙孕素
• 常用英文名：Altrenogest
• CAS号：850-52-2
• 分子式：C₂₁H₂₆O₂
• 分子量：310.430
• 相关类别： 生物化工 抑制剂 内分泌及激素(Endocrinology & Hormones) Estrogen/progestogen Receptor 激动剂
• 发布时间：2018-05-20 08:00:00
• 更新时间：2024-01-02 14:55:24
• 类别 ：有毒物品
  可燃性危险特性 ：可燃;燃烧产生刺激烟雾
  储运特性 ：库房通风低温干燥; 与食品原料分开存放
  灭火剂 ：干粉、泡沫、砂土、二氧化碳, 雾状水

名称

• 中文名: 四烯雌酮
• 英文名: Altrenogest
• 中文别名: 四烯雌酮,烯丙孕素; 烯丙孕素; D9-4-氨基联苯; 烯炳孕素
• 英文别名: (17b)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; 13b-Methyl-17a-allyl-D4,9,11-gonatriene-17b-ol-3-one; (17β)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; Estra-4,9,11-trien-3-one, 17-hydroxy-17-(2-propen-1-yl)-, (17β)-; Allyltrenbolone; r2267; 17α-Allyl-17-hydroxyestra-4,9,11-trien-3-one; altregonest; (17β)-17-hydroxy-17-(prop-2-en-1-yl)estra-4,9,11-trien-3-one; Altrenogest; REGU-MATE; 17-allyltrenbolone; ru2267; Estra-4,9,11-trien-3-one, 17-α-allyl-17-hydroxy-; (8S,13S,14S,17R)-17-Allyl-17-hydroxy-13-methyl-1,2,6,7,8,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one; drc6246; Estra-4,9,11-trien-3-one, 17β-hydroxy-17-(2-propenyl)-; Regumate; 17a-Allyl-17-hydroxyestra-4,9,11-trien-3-one

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 495.6±45.0 °C at 760 mmHg
• 熔点: 120ºC
• 分子式: C₂₁H₂₆O₂
• 分子量: 310.430
• 闪点: 210.1±21.3 °C
• 精确质量: 310.193268
• PSA: 37.30000
• LogP: 3.49
• 外观性状: 固体;White to Yellow powder to crystal
• 蒸汽压: 0.0±2.9 mmHg at 25°C
• 折射率: 1.594
• 储存条件: 库房通风低温干燥,与食品原料分开存放

生物活性

• 描述: Altrenogest(A35957; RU2267)是孕激素,结构与trenbolone相关,能作用于孕激素受体。
• 相关类别:
  信号通路 >> 其他 >> 孕激素受体
  研究领域 >> 内分泌
• 参考文献:

  [1]. Parry-Weeks, L.C. and D.W. Holtan, Effect of altrenogest on pregnancy maintenance in unsynchronized equine embryo recipients. J Reprod Fertil Suppl, 1987. 35: p. 433-8.

  [2]. Daels, P.F., et al., Persistence of the luteal phase following ovulation during altrenogest treatment in mares. Theriogenology, 1996. 46(5): p. 799-811.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KG7745000 CHEMICAL NAME : Estra-4,9,11-trien-3-one, 17-alpha-allyl-17-hydroxy- CAS REGISTRY NUMBER : 850-52-2 LAST UPDATED : 199509 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H26-O2 MOLECULAR WEIGHT : 310.47 WISWESSER LINE NOTATION : L E5 B666 OV AU CU MUTJ E1 FQ F2U1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 3 mg/kg SEX/DURATION : female 18 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders REFERENCE : THGNBO Theriogenology. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1974- Volume(issue)/page/year: 16,195,1981 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 2500 ug/kg SEX/DURATION : female 10 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders REFERENCE : JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W. Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year: 70,1357,1992 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 810 ug/kg SEX/DURATION : female 15 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Maternal Effects - other effects REFERENCE : JRFSAR Journal of Reproduction and Fertility, Supplement. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) No.1- 1966- Volume(issue)/page/year: 32,193,1982

安全

• WGK德国: 3.0
• RTECS号: KG7745000
• 海关编码: 2937290090

海关

海关编码	2937290090