中文名 | 甘草查尔酮B |
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英文名 | (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
中文别名 | 甘草查而酮B |
英文别名 |
2-methoxy-3,4,4'-trihydroxychalcone
Licochalcone B Licochalcon B (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- licochalcone |
描述 | Licochalcone B 是从 Glycyrrhiza inflate 根中提取的。Licochalcone B 抑制淀粉样蛋白 β (amyloid β; Aβ420) 自聚集作用 (IC50=2.16 μM) 并分解预先形成的 Aβ42 原纤维,通过螯合金属离子减少金属诱导的 Aβ42 聚集。 |
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参考文献 |
密度 | 1.4±0.1 g/cm3 |
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沸点 | 550.5±50.0 °C at 760 mmHg |
熔点 | 196-197ºC |
分子式 | C16H14O5 |
分子量 | 286.279 |
闪点 | 208.5±23.6 °C |
精确质量 | 286.084137 |
PSA | 86.99000 |
LogP | 2.57 |
蒸汽压 | 0.0±1.5 mmHg at 25°C |
折射率 | 1.684 |
储存条件 | 2-8C |
~% 58749-23-8 |
文献:Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
~% 58749-23-8 |
文献:Islam, Azizul; Khan, Saeed Ahmad; Krishnamurti, M. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 965 - 966 |
~% 58749-23-8 |
文献:Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
~% 58749-23-8 |
文献:Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
~% 58749-23-8 |
文献:Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 10 p. 965 - 966 |
~% 58749-23-8 |
文献:Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 1 p. 181 - 185 |
上游产品 6 | |
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下游产品 0 |