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25953-17-7生产厂家

25953-17-7价格

25953-17-7

25953-17-7结构式
25953-17-7结构式

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中文名 4-甲基-N-(2-吗啉-4-乙基)-6-苯基吡嗪-3-胺
英文名 minaprine hydrochloride
英文别名 Ag 620
Agr 620
Pyridazine, 4-methyl-3-[(2-morpholinoethyl)amino]-6-phenyl-, dihydrochloride
Agr 1240
4-Morpholineethanamine,N-(4-methyl-6-phenyl-3-pyridazinyl)-,dihydrochloride
Morpholine,4-[2-[(4-methyl-6-phenyl-3-pyridazinyl)amino]ethyl]-,dihydrochloride
Minaprine (dihydrochloride)
沸点 531.2ºC at 760 mmHg
分子式 C17H24Cl2N4O
分子量 371.30
闪点 275.1ºC
PSA 50.28000
LogP 3.00900
蒸汽压 2.29E-11mmHg at 25°C
储存条件 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QE3477835
CHEMICAL NAME :
4-Morpholineethanamine, N-(4-methyl-6-phenyl-3-pyridazinyl)-, dihydrochloride
CAS REGISTRY NUMBER :
25953-17-7
LAST UPDATED :
199707
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C17-H22-N4-O.2Cl-H
MOLECULAR WEIGHT :
371.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,824,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
63 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4508720 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4823 mg/kg/13W-I
TOXIC EFFECTS :
Endocrine - changes in adrenal weight Endocrine - changes in thymus weight
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 24,1894,1990